There are
1,305 mi
from Sioux City, IA to Orangeburg, SC
That's the driving distance. It would take 1 day to go from Sioux City, Iowa to Orangeburg, South Carolina.
The flight distance (direct flight from Sioux City, IA to Orangeburg, SC) is 1,047.82 mi.
1,305 mi = 1.61 kms