There are
1,075 mi
from Sioux City, IA to Opelika, AL
That's the driving distance. It would take 20 hours 49 mins to go from Sioux City, Iowa to Opelika, Alabama.
The flight distance (direct flight from Sioux City, IA to Opelika, AL) is 908.30 mi.
1,075 mi = 1.61 kms