There are
353 mi
from Sioux City, IA to Muscatine, IA
That's the driving distance. It would take 6 hours 32 mins to go from Sioux City, Iowa to Muscatine, Iowa.
The flight distance (direct flight from Sioux City, IA to Muscatine, IA) is 285.03 mi.
353 mi = 567.34 kms