There are
1,268 mi
from Sioux City, IA to Middletown, DE
That's the driving distance. It would take 23 hours 51 mins to go from Sioux City, Iowa to Middletown, Delaware.
The flight distance (direct flight from Sioux City, IA to Middletown, DE) is 1,096.48 mi.
1,268 mi = 1.61 kms