There are
772 mi
from Sioux City, IA to Hopkinsville, KY
That's the driving distance. It would take 14 hours 20 mins to go from Sioux City, Iowa to Hopkinsville, Kentucky.
The flight distance (direct flight from Sioux City, IA to Hopkinsville, KY) is 612.67 mi.
772 mi = 1,242.59 kms