There are
1,415 mi
from Sioux City, IA to Holyoke, MA
That's the driving distance. It would take 1 day 2 hours to go from Sioux City, Iowa to Holyoke, Massachusetts.
The flight distance (direct flight from Sioux City, IA to Holyoke, MA) is 1,210.62 mi.
1,415 mi = 1.61 kms