There are
1,345 mi
from Sioux City, IA to Henderson, NV
That's the driving distance. It would take 23 hours 38 mins to go from Sioux City, Iowa to Henderson, Nevada.
The flight distance (direct flight from Sioux City, IA to Henderson, NV) is 1,086.52 mi.
1,345 mi = 1.61 kms