There are
1,244 mi
from Sioux City, IA to Harlingen, TX
That's the driving distance. It would take 22 hours 17 mins to go from Sioux City, Iowa to Harlingen, Texas.
The flight distance (direct flight from Sioux City, IA to Harlingen, TX) is 1,129.25 mi.
1,244 mi = 1.61 kms