There are
388 mi
from Sioux City, IA to Great Bend, KS
That's the driving distance. It would take 7 hours 26 mins to go from Sioux City, Iowa to Great Bend, Kansas.
The flight distance (direct flight from Sioux City, IA to Great Bend, KS) is 311.59 mi.
388 mi = 625.08 kms