There are
1,411 mi
from Sioux City, IA to Gainesville, FL
That's the driving distance. It would take 1 day 2 hours to go from Sioux City, Iowa to Gainesville, Florida.
The flight distance (direct flight from Sioux City, IA to Gainesville, FL) is 1,182.42 mi.
1,411 mi = 1.61 kms