There are
784 mi
from Sioux City, IA to Clarksville, IN
That's the driving distance. It would take 14 hours 14 mins to go from Sioux City, Iowa to Clarksville, Indiana.
The flight distance (direct flight from Sioux City, IA to Clarksville, IN) is 630.06 mi.
784 mi = 1,261.43 kms