There are
858 mi
from Sioux City, IA to Chillicothe, OH
That's the driving distance. It would take 15 hours 58 mins to go from Sioux City, Iowa to Chillicothe, Ohio.
The flight distance (direct flight from Sioux City, IA to Chillicothe, OH) is 733.01 mi.
858 mi = 1,381.57 kms