There are
528 mi
from Sioux City, IA to Cheyenne, WY
That's the driving distance. It would take 9 hours 49 mins to go from Sioux City, Iowa to Cheyenne, Wyoming.
The flight distance (direct flight from Sioux City, IA to Cheyenne, WY) is 443.40 mi.
528 mi = 849.49 kms