There are
508 mi
from Sioux City, IA to Chesterfield, MO
That's the driving distance. It would take 9 hours 26 mins to go from Sioux City, Iowa to Chesterfield, Missouri.
The flight distance (direct flight from Sioux City, IA to Chesterfield, MO) is 404.36 mi.
508 mi = 817.13 kms