There are
1,645 mi
from Sioux City, IA to Calexico, CA
That's the driving distance. It would take 1 day 5 hours to go from Sioux City, Iowa to Calexico, California.
The flight distance (direct flight from Sioux City, IA to Calexico, CA) is 1,242.01 mi.
1,645 mi = 1.61 kms