There are
2,302 mi
from Simi Valley, CA to Waynesville, NC
That's the driving distance. It would take 1 day 16 hours to go from Simi Valley, California to Waynesville, North Carolina.
The flight distance (direct flight from Simi Valley, CA to Waynesville, NC) is 2,019.36 mi.
2,302 mi = 3.22 kms