There are
1,847 mi
from Simi Valley, CA to Maryland Heights, MO
That's the driving distance. It would take 1 day 8 hours to go from Simi Valley, California to Maryland Heights, Missouri.
The flight distance (direct flight from Simi Valley, CA to Maryland Heights, MO) is 1,597.80 mi.
1,847 mi = 1.61 kms