There are
410 mi
from Simi Valley, CA to Glendale, AZ
That's the driving distance. It would take 7 hours 31 mins to go from Simi Valley, California to Glendale, Arizona.
The flight distance (direct flight from Simi Valley, CA to Glendale, AZ) is 381.48 mi.
410 mi = 660.17 kms