There are
2,041 mi
from Simi Valley, CA to Antioch, IL
That's the driving distance. It would take 1 day 12 hours to go from Simi Valley, California to Antioch, Illinois.
The flight distance (direct flight from Simi Valley, CA to Antioch, IL) is 1,744.98 mi.
2,041 mi = 3.22 kms