There are
1,461 mi
from Sedona, AZ to Tupelo, MS
That's the driving distance. It would take 1 day 1 hour to go from Sedona, Arizona to Tupelo, Mississippi.
The flight distance (direct flight from Sedona, AZ to Tupelo, MS) is 1,309.72 mi.
1,461 mi = 2,350.96 kms