There are
2,411 mi
from Santee, CA to Zephyrhills, FL
That's the driving distance. It would take 1 day 18 hours to go from Santee, California to Zephyrhills, Florida.
The flight distance (direct flight from Santee, CA to Zephyrhills, FL) is 2,085.38 mi.
2,411 mi = 3,880.46 kms