There are
2,435 mi
from Santee, CA to Thomasville, NC
That's the driving distance. It would take 1 day 18 hours to go from Santee, California to Thomasville, North Carolina.
The flight distance (direct flight from Santee, CA to Thomasville, NC) is 2,102.25 mi.
2,435 mi = 3,918.49 kms