There are
1,248 mi
from Santee, CA to Seatac, WA
That's the driving distance. It would take 23 hours 44 mins to go from Santee, California to Seatac, Washington.
The flight distance (direct flight from Santee, CA to Seatac, WA) is 1,047.92 mi.
1,248 mi = 2,009.04 kms