There are
2,046 mi
from Santee, CA to Oswego, IL
That's the driving distance. It would take 1 day 11 hours to go from Santee, California to Oswego, Illinois.
The flight distance (direct flight from Santee, CA to Oswego, IL) is 1,678.75 mi.
2,046 mi = 3,292.69 kms