There are
2,075 mi
from Santee, CA to Midlothian, IL
That's the driving distance. It would take 1 day 12 hours to go from Santee, California to Midlothian, Illinois.
The flight distance (direct flight from Santee, CA to Midlothian, IL) is 1,710 mi.
2,075 mi = 3,339.64 kms