There are
2,716 mi
from Santee, CA to Lansdowne, PA
That's the driving distance. It would take 2 days to go from Santee, California to Lansdowne, Pennsylvania.
The flight distance (direct flight from Santee, CA to Lansdowne, PA) is 2,348.75 mi.
2,716 mi = 4,370.95 kms