There are
1,728 mi
from Santa Maria, CA to South Sioux City, NE
That's the driving distance. It would take 1 day 6 hours to go from Santa Maria, California to South Sioux City, Nebraska.
The flight distance (direct flight from Santa Maria, CA to South Sioux City, NE) is 1,389.39 mi.
1,728 mi = 1.61 kms