There are
2,121 mi
from Santa Maria, CA to Madisonville, KY
That's the driving distance. It would take 1 day 14 hours to go from Santa Maria, California to Madisonville, Kentucky.
The flight distance (direct flight from Santa Maria, CA to Madisonville, KY) is 1,835.84 mi.
2,121 mi = 3.22 kms