There are
1,237 mi
from Santa Fe, NM to Owensboro, KY
That's the driving distance. It would take 22 hours to go from Santa Fe, New Mexico to Owensboro, Kentucky.
The flight distance (direct flight from Santa Fe, NM to Owensboro, KY) is 1,050.64 mi.
1,237 mi = 1,990.62 kms