There are
1,290 mi
from Santa Fe, NM to Cookeville, TN
That's the driving distance. It would take 22 hours 33 mins to go from Santa Fe, New Mexico to Cookeville, Tennessee.
The flight distance (direct flight from Santa Fe, NM to Cookeville, TN) is 1,141.80 mi.
1,290 mi = 1.61 kms