There are
1,799 mi
from Santa Cruz, CA to Sioux Falls, SD
That's the driving distance. It would take 1 day 7 hours to go from Santa Cruz, California to Sioux Falls, South Dakota.
The flight distance (direct flight from Santa Cruz, CA to Sioux Falls, SD) is 1,404.18 mi.
1,799 mi = 2,895.91 kms