There are
2,990 mi
from Santa Cruz, CA to Poughkeepsie, NY
That's the driving distance. It would take 2 days 4 hours to go from Santa Cruz, California to Poughkeepsie, New York.
The flight distance (direct flight from Santa Cruz, CA to Poughkeepsie, NY) is 2,558.09 mi.
2,990 mi = 4,811.32 kms