There are
1,803 mi
from Santa Cruz, CA to Neosho, MO
That's the driving distance. It would take 1 day 7 hours to go from Santa Cruz, California to Neosho, Missouri.
The flight distance (direct flight from Santa Cruz, CA to Neosho, MO) is 1,522.61 mi.
1,803 mi = 2,901.59 kms