There are
2,849 mi
from Santa Cruz, CA to Ithaca, NY
That's the driving distance. It would take 2 days 2 hours to go from Santa Cruz, California to Ithaca, New York.
The flight distance (direct flight from Santa Cruz, CA to Ithaca, NY) is 2,419.97 mi.
2,849 mi = 4,585.23 kms