There are
1,864 mi
from Santa Ana, CA to Keokuk, IA
That's the driving distance. It would take 1 day 8 hours to go from Santa Ana, California to Keokuk, Iowa.
The flight distance (direct flight from Santa Ana, CA to Keokuk, IA) is 1,523.47 mi.
1,864 mi = 1.61 kms