There are
2,424 mi
from San Mateo, CA to Wilmington, OH
That's the driving distance. It would take 1 day 18 hours to go from San Mateo, California to Wilmington, Ohio.
The flight distance (direct flight from San Mateo, CA to Wilmington, OH) is 2,069.80 mi.
2,424 mi = 3.22 kms