There are
2,874 mi
from San Mateo, CA to Wilmington, NC
That's the driving distance. It would take 2 days 2 hours to go from San Mateo, California to Wilmington, North Carolina.
The flight distance (direct flight from San Mateo, CA to Wilmington, NC) is 2,471.84 mi.
2,874 mi = 4,624.47 kms