There are
3,120 mi
from San Mateo, CA to Watertown, MA
That's the driving distance. It would take 2 days 7 hours to go from San Mateo, California to Watertown, Massachusetts.
The flight distance (direct flight from San Mateo, CA to Watertown, MA) is 2,687.62 mi.
3,120 mi = 4.83 kms