There are
1,928 mi
from San Mateo, CA to Waterloo, IA
That's the driving distance. It would take 1 day 9 hours to go from San Mateo, California to Waterloo, Iowa.
The flight distance (direct flight from San Mateo, CA to Waterloo, IA) is 1,613.54 mi.
1,928 mi = 1.61 kms