There are
2,305 mi
from San Mateo, CA to Tuscaloosa, AL
That's the driving distance. It would take 1 day 16 hours to go from San Mateo, California to Tuscaloosa, Alabama.
The flight distance (direct flight from San Mateo, CA to Tuscaloosa, AL) is 1,969.44 mi.
2,305 mi = 3,710.00 kms