There are
856 mi
from San Mateo, CA to Tucson, AZ
That's the driving distance. It would take 15 hours 40 mins to go from San Mateo, California to Tucson, Arizona.
The flight distance (direct flight from San Mateo, CA to Tucson, AZ) is 743.24 mi.
856 mi = 1,376.84 kms