There are
2,394 mi
from San Mateo, CA to Trenton, OH
That's the driving distance. It would take 1 day 17 hours to go from San Mateo, California to Trenton, Ohio.
The flight distance (direct flight from San Mateo, CA to Trenton, OH) is 2,036.25 mi.
2,394 mi = 3.22 kms