There are
2,827 mi
from San Mateo, CA to Takoma Park, MD
That's the driving distance. It would take 2 days 1 hour to go from San Mateo, California to Takoma Park, Maryland.
The flight distance (direct flight from San Mateo, CA to Takoma Park, MD) is 2,434.60 mi.
2,827 mi = 3.22 kms