There are
2,095 mi
from San Mateo, CA to Southaven, MS
That's the driving distance. It would take 1 day 12 hours to go from San Mateo, California to Southaven, Mississippi.
The flight distance (direct flight from San Mateo, CA to Southaven, MS) is 1,799.80 mi.
2,095 mi = 3.22 kms