There are
1,758 mi
from San Mateo, CA to Sioux Falls, SD
That's the driving distance. It would take 1 day 6 hours to go from San Mateo, California to Sioux Falls, South Dakota.
The flight distance (direct flight from San Mateo, CA to Sioux Falls, SD) is 1,400.92 mi.
1,758 mi = 1.61 kms