Miles between San Mateo, CA and Santa Ana, CA

There are
401 mi
from San Mateo, CA to Santa Ana, CA

That's the driving distance. It would take 7 hours 36 mins to go from San Mateo, California to Santa Ana, California.

The flight distance (direct flight from San Mateo, CA to Santa Ana, CA) is 363.51 mi.

401 mi = 645.62 kms