There are
2,425 mi
from San Mateo, CA to Sandusky, OH
That's the driving distance. It would take 1 day 18 hours to go from San Mateo, California to Sandusky, Ohio.
The flight distance (direct flight from San Mateo, CA to Sandusky, OH) is 2,110.44 mi.
2,425 mi = 3.22 kms