There are
3,213 mi
from San Mateo, CA to Saco, ME
That's the driving distance. It would take 2 days 9 hours to go from San Mateo, California to Saco, Maine.
The flight distance (direct flight from San Mateo, CA to Saco, ME) is 2,710.81 mi.
3,213 mi = 4.83 kms