There are
2,691 mi
from San Mateo, CA to Radford, VA
That's the driving distance. It would take 1 day 23 hours to go from San Mateo, California to Radford, Virginia.
The flight distance (direct flight from San Mateo, CA to Radford, VA) is 2,274.11 mi.
2,691 mi = 3.22 kms