There are
2,948 mi
from San Mateo, CA to Poughkeepsie, NY
That's the driving distance. It would take 2 days 3 hours to go from San Mateo, California to Poughkeepsie, New York.
The flight distance (direct flight from San Mateo, CA to Poughkeepsie, NY) is 2,557.66 mi.
2,948 mi = 3.22 kms